Posts by Assaf Sagiv
Novel Drug for Glaucoma Treatment
The Problem Glaucoma is one of the leading causes of blindness in the world. It is a slow and progressive disease that can lead to vision loss over a long period of time. Over 60 million people worldwide lives with glaucoma using multiple therapies in order to prevent blindness- and the patients’ number will grow…
Read MoreNovel Peptides for Treating Cocaine Addiction And Pain
The Problems Drug addiction is a scourge of both developed and less-developed societies. The economic impact of drug addiction includes direct treatment costs as well as lost productivity and crime. Neuropathic pain is a chronic pain condition caused by a primary lesion or dysfunction in the nervous system. It can be a consequence of many different…
Read MoreSurface Engineering & Disaggregation Features of Strong Hardness Chemically Stable Nanodiamonds
The Problem The two major pain points of fully bio-compatible non-toxic carbon-based mechanically hard 4-10 nm-sized nanomaterials (nanodiamonds-NDs) are their high reaction times and their extreme-sized methodologies. These two lead to very difficult surface-functionalizing in a versatile manner for a wide range of full various domains applications. The Solution Our innovation successfully discovered that extremely…
Read MorePrevention and Treatment of Viral Infections with Nano-particles Capped with Functional Groups
The Problem Viral infections continuously take place and pose major public health threats; yet, their prevention and treatment modalities are limited while emerging resistant viruses call for the development of alternative treatments. The Solution We developed a novel approach for the prevention and treatment of infections caused by viruses which attach cells via heparan sulfate binding,…
Read MoreNovel 64cu(Ii) Radiotracer For Diagnostic Of Hypoxia
The Problem The development of a biomarker for hypoxic tissues is essential both for diagnostic formulation and treatment planning for most cancer patients. Although the current PET radiotracers are non-invasive imaging modality techniques of tumor hypoxia, they are not being used routinely due to slow uptake by hypoxic. Cu(II)-tracers have been suggested to become one…
Read MoreImproved Tumor Margins Detection Using Gold Nano-rods
The Problem Most optical-physiological diagnoses are based on the insertion of light, with known parameters, to a tested tissue, followed by the measurement of the reflected, transmitted, or absorbed light. Changes in the optical properties of this light such as its spectrum, polarization, or intensity, compared to the injected light, result from interactions of the…
Read MoreMetabolic Imaging Of Cancer Using CT
The Problem Current conventional structural diagnostic modalities do not detect evident of cancer lesions at early stages as they are not cancer-specific. The Solution The functional imaging FDG-PET provides the ability to visualize cancer cells based on their increased glucose metabolic activity and can detect tumor presence at early stages that conventional structural diagnostic modalities…
Read MoreGlucose Conjugated Gold Nano-particles for Cancer Detection
The Problem Cancer detection is currently based on two insufficient imaging techniques: structural and functional. While structural techniques identify anatomic details and provide information on tumor location, size, and spread, based on endogenous contrast, they are ineffective in detecting critical small tumors or metastases.The main functional imaging technique, FDG-PET, is based on increased glucose metabolic activity…
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