Surface Engineering & Disaggregation Features of Strong Hardness Chemically Stable Nanodiamonds
The Problem
The two major pain points of fully bio-compatible non-toxic carbon-based mechanically hard 4-10 nm-sized nanomaterials (nanodiamonds-NDs) are their high reaction times and their extreme-sized methodologies. These two lead to very difficult surface-functionalizing in a versatile manner for a wide range of full various domains applications.
The Solution
Our innovation successfully discovered that extremely chemically versatile lanthanide actions/complexes may be successfully used for NDs surface engineering and successful parallel disaggregation when using both fluorescent and non-fluorescent NDs.
The Commercial Benefit
Our outstanding solution introduces extreme nanofabrication versatility potential for a wide range of functional fluorescent and non-fluorescent NDs. Moreover, it proposes a significantly improved disaggregation feature when compared with currently commercially available NDs.
Market Potential
The global nanomaterials market stood at US$ 7.3 billion in 2016. Witnessing a tremendous rise during the period from 2017 to 2022, the revenue in this nanomaterials market is expected to reach US$ 16.8 billion by the end of the forecast period. The main types available in this nanomaterials market are chemicals & polymers, metal oxide, and metals. Among the three, the demand for chemicals & polymers is relatively higher and the trend is anticipated to remain so over the next few years, notes the nanomaterials market research report.
Target Markets/Industries
- Biology-based markets/industries,
- Cosmetics-relating ones
- Human disease therapy (gene delivery/imaging (in vivo fluorescence), anti-bacterial, &
- Potential Nanoscale Sensing-based applications
- Improved lubrication, tools binders, polymeric film coatings-based ones
- Long-term cell imaging (including stem cells)
- Bioassays
- Super-resolution & correlative microscopy imaging (fiducial markers)
- Nanosensors
- Labeling in tissue engineering
- Image-guided surgery
Intellectual Property
Patent application pending (PCT/IL2020/051218)
Team: Primary Inventor
Prof. Jean-Paul Lellouche
- Prof. Jean-Paul (Moshe) Lellouche is the Head of the Department of Chemistry and the Nano Materials Center at the Institute of Nanotechnology and Advanced Materials (BINA).
- Prof. Lellouche's s main research interests include the chemical design, surface engineering, fabrication, and characterization of a wide range of functional organic and inorganic nanomaterials for various energy, biomedicine, conductivity, mechanical/lubricant-improvement methodologies, and (bio) sensing-driven applications.
- Lellouche has authored 149 peer-reviewed papers, 15 patents and 3 book chapters while
attracting more than US$ 6,581,000 in external grant funding.
Future Research
- Development of theranostic functional nanodiamonds
- Novel nanodiamond-based drug delivery/imaging/PDT photodynamic therapy/gene
silencing nanosystems (in vivo anti-cancer bioactivity & cell tracking for example) - Innovative more effective skin-penetration of functional bioactive cosmetic creams (anti-parasitic ones for example)
- Development of corresponding biosensing nanodiamonds
- Nanodiamond-based protective 3D printed coatings
The Opportunity
We offer licensing of our patent sponsored research to qualified companies
