255 innovations from Bar-Ilan University, available for licensing, co-investment, or spin-out through BIRAD.
Tischler Yaakov Raphael
The invention is an unmanned aerial vehicle (UAV) platform physically and optically linked to a remote base station via a flexible, high-bandwidth optical fiber tether. The architecture decouples the heavy, high-cost, and environmentally sensitive components of a spectroscopic system (such as high-power pulsed/tunable laser engines, complex modulation optics, and laboratory-grade spectrographs or gas-phase analysis hardware) from the mobile flight platform. The flexible tether is optimized for advanced optical transport, supporting single-fiber configurations (utilizing co-axial transceiver optics or double-clad fibers to route both excitation and collection paths through a single line) or multi-fiber bundles (separating excitation and collection lines). To eliminate fiber-induced background noise and accommodate ultra-fast pulses, the system incorporates hollow-core photonic crystal fibers (HC-PCFs), or alternatively utilizes standard, cost-effective solid silica fibers combined with an on-board micro-optical filtering payload head on the UAV. This payload head incorporates high-performance laser cleanup bandpass filters that actively strip away fiber-induced silica Raman sideband spectral peaks and autofluorescence before the excitation light hits the target, alongside longpass/notch/shortpass edge filters that isolate the target's weak spectroscopic signals from backscattered pump light. The UAV payload head features a dynamically adjustable optical delivery system capable of switching between a tightly focused beam configuration (for high-power density point-and-shoot spectroscopy like spontaneous/resonance Raman or LIBS) and a collimated beam configuration (for wide-area illumination, plume absorption, or thermal-ignition mitigation of sensitive energetics). Additionally, the drone features an extractive sampling configuration containing an enclosed internal gas cell for high-precision Cavity Ring-Down Spectroscopy (CRDS) or Tunable Diode Laser Absorption Spectroscopy (TDLAS). To operate in intense ambient-light environments (such as bright daylight) without blinding the spectrometer, the system incorporates distributed optical and electronic noise-suppression packages. These include: An excitation/collection package using ultra-fast time-gating to physically slice out daylight; A spectral-modulation package utilizing Shifted Excitation Raman Difference Spectroscopy (SERDS) under both continuous-wave and pulsed regimes to mathematically subtract invariant background light; and A payload-filtering package on the UAV utilizing tunable Fabry-Pérot etalons or narrow-band collection filters to isolate the signal before it propagates down the return line. The system also supports hybrid photo-acoustic and laser Doppler vibrometry (LDV) tracking, using phase-locked lock-in demodulation distributed on-board or down-fiber to isolate target signatures from UAV motor and rotor noises.
Klein Shmuel Tomi
Huffman coding is one of the best known compression methods. Its static variant encodes each occurrence of a given character in the same way throughout the process, which is known to produce an optimal encoding. A dynamic variant of Huffman coding encodes a given character on the basis of its frequency in the portion of the input file processed so far. Dynamic Huffman coding may be better than static Huffman coding, but it may also be worse. The new method proposed in this invention is provably always better than the static variant of Huffman coding. This is achieved by reversing the direction for the references of the encoded elements to those forming the model of the encoding, from pointing backwards to looking into the future.
Gonen, Nitzan
We have generated testis organoids from embryonic and neonatal mouse testicular cells. We use transwell inserts and well defined media for this. The organoids can be maintained for 9 weeks in vitro and preserve all main testicular cell types. They also display gene expression profiles that are highly similar to the real testis as well as spatial organisation that resemble the testis. We also developed 2 defined media compositions that enable to support the immature versus mature testis states.
Aurbach Doron
High energy cathode for lithium sulfur cell. Current collector with a two-layer structure consisting of a layer with low areal electronic resistance (e.g., C-coated metal Al) and a layer with a porous structure (e.g., carbon paper) adhered on top. Cathode for lithium sulfur batteries containing two types of binder, swell-able and non-swellable, in the electrode plate, and the two types of binder are arranged in a layered configuration. "
Noked Malachi
In the present work, we purpose to achieve cobalt-free high capacity cathode for Na-ion batteries using high entropy approach. High entropy approach comprises the mixing of more than five elements in a single phase which itself is a challenge as it involves interplay between different elements to get the desired properties. Here, Li is introduced in the composition to get high configurational entropy that offers Na vacant sites, hence stabilizes the crystal structure by entropy stabilization, accelerate the kinetics and improves the air stability. With the optimization in the composition of cathode, a reversible capacity of 109 mAh g-1 (2-4V) and 144 mAh g-1 (2-4.3V) is observed in first few cycles with a significant stability during prolong cycling. Further, insitu and exsitu diffraction studies during charging and discharging has revealed that the high entropy strategy is successful in overcoming the complex phase transition in O3 layered structure by suppressing the O3’ phase. The impressive outcomes of the present work strongly motivate to pursue high entropy approach in developing efficient cathode for Na-ion batteries.
Cohen Eliahu
A system and apparatus for high-resolution, high-contrast and low-dose imaging using high-photon energy radiation in the hard X-ray and gamma-ray regimes. The system comprises of A) a high-photon energy source configured to provide an input beam; B) a diffuser configured to induce intensity fluctuations that are stronger than the intensity fluctuations originating from the source i) the diffuser is predesigned and fabricated according to a computer generated topographic map; ii) the diffuser is characterized by a high-resolution imaging system; C) motorized stages to scan the diffuser: D) a detector which can be either a low-resolution detector or a single-pixel detector, and E) a processor configured to receive output intensity measurements, to correlate the output intensity measurements with the intensity fluctuations at the position of the object calculated from the knowledge on the diffuser details, and to use the correlated data to reconstruct an image of the object.
Lindell Yehuda
High Throughput Secure Multi-Party Computation With Identifiable Abort
Peer Avraham
We present a novel configuration for a mode-locked semiconductor laser oscillator that emits picosecond-to femtosecond range pulses with record pulse energy (0.5nJ demonstrated) and peak power (112W demonstrated) directly out of the oscillator (with no amplifier). To achieve this high power performance, which is about 20 times higher than other published results with similar lasers, we employed a high-current broad-area, spatially multi-mode diode amplifier, placed in an external cavity that enforces oscillation in a single spatial mode. Consequently, the brightness of the beam can be near-ideal (close to M2 = 1). Mode locking is achieved by dividing the large diode chip (edge emitter) into two sections with independent electrical control: one large section for gain and another small section for a saturable absorber. Precise tuning of the reverse voltage on the absorber section allows to tune the saturation level and recovery time of the absorber, providing a convenient knob to optimize the mode-locking performance for various cavity conditions.
Mandel Yossi
The invention is a new device and method that enables a better interface between electrodes and patients’ (or other) neural tissue, such as the retina. The invention is based on high-density electrode array integrated with glutamatergic (or other) cells. Upon implantation of the device into the subretinal space of patients suffering from retinal degeneration (e.g.; age-related macular degeneration) the neurons synapse with the host retina. Activation of individual neurons by electric field elicits activation of the host retina with natural characteristics and restores vision at resolution and quality near normal vision.
Tischler Yaakov Raphael
A compact, modular hybrid super-resolution optical spectrometer applicable to a broad range of optical spectroscopy modalities (e.g., Raman, IR, absorption, and emission), combining coarse dispersive selection with high-finesse interferometric spectral encoding. A diffraction grating provides coarse spectral selection and/or order sorting and may be operated in a stationary mode or with controlled dithering to impose a small periodic spectral shift. A high-finesse optical filter, such as a Fabry–Pérot (F-P) etalon, provides narrowband super-resolution selectivity and is scanned and/or encoded via angle tuning and/or modulation on a precision stage; modulation may be applied to the grating, the etalon, or both. The optical signal is split into two simultaneous channels: a primary measurement channel (e.g., an etalon-transmitted channel) and a radiometric reference channel used for normalization. Synchronous detection (e.g., lock-in demodulation referenced to the applied modulation) extracts the modulated spectral component, yielding a differential and/or derivative-like signal that rejects broadband background (including fluorescence in Raman implementations) and improves robustness to power fluctuations, coupling changes, and system drift. The spectrometer is capable of detecting signals generated by optical excitation or by other means of energizing the sample of interest. In some implementations, the excitation source may be a laser operating in either continuous-wave (CW) mode, delivering a relatively constant level of power to the sample, or in pulsed mode, in which the excitation is delivered as bursts of light. The present spectrometer architecture is also naturally compatible with pulsed excitation and time-gated detection, in that the grating and narrowband optical filter can receive emission generated by pulsed excitation and pass it to a time-gated detector or CCD. Pulsed excitation may be advantageous, for example, for monitoring fast processes and tracking spectral changes as a material evolves over time, and also for temporally discriminating Raman emission from slower fluorescence background. When pulsed excitation and gated detection are combined with dispersion modulation as described herein, an additional level of background suppression may be achieved. As a result, useful suppression levels may in some cases be obtained even with slower pulsed lasers than would otherwise be required. In another implementation, a femtosecond pulsed laser is used, and the pulse is filtered before entering the spectrometer in order to stretch or shape the pulse. Such pulse shaping is achieved using a spatial light modulator (SLM) or a Fabry–Pérot etalon. The etalon is held at a fixed orientation or operated with angular modulation. Passing a broadband femtosecond pulse through the etalon converts it into a series of spectrally narrower pulses. The Raman signal generated by such excitation correspondingly appears as a spectral pulse train. This is advantageous because the spectral pulse train shifts across the CCD as the grating is modulated, while background signals remain relatively stationary. In addition, the overall pulse duration remains much shorter than typical fluorescence lifetimes, such that time-gated detection further helps reject spurious background signals.
Zalevsky Zeev
Time multiplexing is a super resolution technique that sacrifices time to overcome the resolution reduction obtained because of diffraction. There are many super resolution methods based on time multiplexing, but all of them require a priori knowledge of the time changing encoding mask, which is projected on the object and used to encode and decode the high-resolution information. In this paper, we present a time multiplexing technique that does not require the a priori knowledge on the projected encoding mask. First, the theoretical concept of the technique is demonstrated, then, numerical simulations and experimental results are presented.
Louzoun Yoram
We have developed a novel machine learning for microbiome based classification. The method is based on the translation of samples into images and applying CNN to these images
