83 innovations from Bar-Ilan University, available for licensing, co-investment, or spin-out through BIRAD.
Salomon Adi
The META-SERS-NET substrates described herein provide a versatile, scalable, and highly sensitive platform for Surface-Enhanced Raman Scattering (SERS) detection of a wide range of organic and inorganic analytes in aqueous environments. Owing to their three-dimensional nanostructured architecture, broad electromagnetic enhancement, negligible background, and compatibility with lightweight machine-learning (ML) models, these metasurfaces are suitable for multiple commercial and industrial applications, including but not limited to: Environmental Monitoring and Water Quality Control META-SERS-NET substrates are designed for rapid, label-free detection of organic contaminants (e.g., dyes, pesticides, pharmaceuticals) and inorganic ions (e.g., Li⁺, Mg²⁺, B⁺, Na⁺) directly in water. The high enhancement factor, combined with the ability to detect analytes at concentrations down to 10⁻⁹ M, enables: Salomon_SERS_Spec_V3-M Online and offline monitoring of drinking water quality. Surveillance of industrial effluents, wastewater treatment plants, and surface waters. Early detection of persistent organic pollutants and heavy-metal–related species when coupled with appropriate ion-selective polymers. Portable and Field-Deployable Sensing Devices The META-SERS-NET architecture maintains strong SERS performance even when used with low-NA optics (e.g., NA = 0.15), which are typical in portable and handheld Raman instruments. Salomon_SERS_Spec_V3-M This optical tolerance enables: Integration into handheld Raman probes for in-field environmental monitoring. Compact sensors for on-site industrial process control, pipeline monitoring, and spill detection. Low-cost, battery-operated point-of-use devices for municipalities, utilities, and emergency response teams. Industrial Process Control and Quality Assurance The reproducible enhancement and negligible substrate background of META-SERS-NET allow robust quantification of analytes across several orders of magnitude in concentration. Salomon_SERS_Spec_V3-M This makes the platform suitable for: Real-time tracking of dyes, intermediates, and by-products in chemical and pharmaceutical production. Quality control in manufacturing processes requiring precise monitoring of residual contaminants. Inline or at-line sensors for continuous verification of feedstocks, solvents, and process streams. Food and Beverage Safety By enabling sensitive detection of trace dyes, adulterants, and ionic species, META-SERS-NET can be incorporated into: Screening tools for contaminants in beverages and liquid food matrices (e.g., juices, dairy, brewing lines). Rapid verification of cleaning and sanitation processes via detection of residual chemicals in rinse water. Biomedical and Clinical Research Tools (Non-diagnostic Use) In research settings, META-SERS-NET can serve as a high-performance SERS platform for: Studying drug–polymer and ion–polymer interactions using the polymer-assisted detection mode. Salomon_SERS_Spec_V3-M Investigating model bio-relevant ions and small molecules in simulated physiological media. Serving as a robust reference substrate for SERS method development in analytical and bioanalytical laboratories. AI-Augmented Analytical Platforms The integration of the metasurface with a dedicated machine-learning spectral reconstruction module provides enhanced peak separation, noise suppression, and analyte classification. Salomon_SERS_Spec_V3-M This joint optical–computational architecture enables: Automated, high-accuracy detection and quantification of multiple analytes in complex mixtures. Cloud-connected or on-device AI-SERS platforms for routine monitoring tasks operated by non-experts. “Smart” SERS instruments that self-calibrate using the internal Si reference and adapt to device-specific spectral distortions. Calibration Standards and Reference Substrates Due to their ligand-free, additive-free fabrication and high reproducibility over large areas, META-SERS-NET substrates can function as: Salomon_SERS_Spec_V3-M Standard SERS reference substrates for instrument calibration and inter-laboratory comparisons. Internal standards in commercial Raman instruments, ensuring consistent performance across devices and over time. Long-Lifetime, Low-Maintenance Sensing Modules The metasurfaces exhibit lifetimes of at least one year under standard storage and operating conditions and demonstrate efficient heat dissipation and stability at low excitation powers. Salomon_SERS_Spec_V3-M This durability supports: Long-term deployment in remote or difficult-to-access locations. Low-maintenance sensor cartridges for subscription-based monitoring services. Replacement-ready “plug-and-measure” chips that can be exchanged in field devices without complex recalibration.
Naveh Doron
Metal intercalated within the van der Waals gap of layered semiconductor compounds such as MoS2 resulting in a unique hybrid manifesting enhanced interactions with light and consequently result in photodetector devices with improved photoresponse. For example, copper-enhanced MoS2 photodiodes are superior in their spectral response, that extends into the infrared and also in their total responsivity that exceeds 104 A/W. The gain of such photodetectors is comparable with those of night vision enhancing devices.
Naveh Doron
State-of-the-art methods for printing highly resolved pixels of two-dimensional (2D) materials on technologically important substrates typically involve multiple and time-consuming processing steps which increase device fabrication complexity and the risk of impurity contamination. This work introduces an alternative printing approach based on the Laser Induced Forward Transfer (LIFT) technique for the successful digital transfer of graphene, MoS2 hexagonal boron nitride (h-BN) and, Bi2Se(3-x)Sx. Using LIFT, graphene pixels of 30 μm x 30 μm, MoS2 and Bi2Se3 flakes are transferred on SiO2/Si and flexible polymer substrates. The potential of upscaling this novel approach by reaching sizes of up to 300 μm x 300 μm for transferred graphene patches is also demonstrated. The transferred 2D materials are employed for the fabrication of devices including flexible touch sensors and Field-Effect-Transistors. By repeating the printing process also heterostructures of 2D materials can be developed.
Naveh Doron
A method that includes all the fabrication process for making a multilayer printed circuit board when a CVD grown copper-graphene is in presence in the circuit. The method describes the ways to do the fabrication and keeping the graphene intact.
Naveh Doron
The invention includes the integration of multi-layer graphene inside printed cards (PCB) and is designed to help with the solution of power dissipation problems, emitted as heat to the environment . the dissipated heat damage the function of the card and creates a waste of energy. multi-layer graphene known as high thermal conductivity value material (calculated and measured), but has not been integrated into cards or motherboards to date so far.
Gerber Doron
We have invented a microfluidic mechanism that allows us to take any ELISA/antibody based detection assay and improve its sensitivity 2-3 orders of magnitude. This means that we can work with very small samples or discover for example blood markers that are very scarce.
Noked Malachi
Na4Fe3(PO4)2(P2O7) is an emerging cathode material for next-generation Na-ion batteries owing to its environmentally benign nature, cost-effectiveness, and optimal operating potential. However, the sluggish Na-ion kinetics and poor electronic conductivity have hampered its commercialization. This study aims to address these setbacks through a medium-entropy dual-ion doping strategy, in which both cations (V3+, Mn2+) and anions (F–, SO42–, BO33-) are doped via a scalable sol-gel synthesis, forming Na3.64Fe2.94V0.03Mn0.03(PO4)1.94F0.03(BO3)0.03(P2O7) (NFPP-ME-BO3) and Na3.61Fe2.94V0.03Mn0.03(PO4)1.94F0.03(SO4)0.03(P2O7) (NFPP-ME-SO4). Herein, transition-metal (TM) doping enhances electronic conductivity by reducing the gap between the valence and conduction bands, while poly-anion dopants (BO33-, SO42-) act as pillars, improving structural stability and expanding the diffusion channel, thereby facilitating Na-ion diffusion. To demonstrate its practical relevance, full cells were fabricated against hard carbon and Fe3O4 as the anodes.
Shor Joseph
A new concept for Physical Unclonable Functions (PUFs), the Mirror PUF, is proposed. The Mirror PUF can be applied to existing preselected PUF circuits and has the potential to double the number of effective bits, with no additional area at the bit-cell level. The Mirror PUF utilizes a preselection test, which measures the amount of mismatch within the PUF cell. This data is generally used to determine the mask for a conventional PUF. Here, it is used as an entropy source that is not correlated to the original response of the PUF. Bit-cells with low mismatch are considered as a ‘0’ and cells with high mismatch as a ‘1’. A systematic method is shown for identifying unstable bits in the Mirror PUF response. It classifies the cells to ‘low’, ‘medium’ and ‘high’ mismatch, such that medium mismatch bits are considered as unstable and masked from the response. The concept was applied to a 65nm Si implementation of the Capacitive Tilt PUF [1]. All of the unstable cells of the Mirror PUF, except for 0.03%, were identified and masked, with only 0.0003% erroneous responses. The application of the Mirror PUF to the Capacitive tilt PUF increased the number of stable response bits by 63%. No observable correlation was found between the responses of the original PUF and the Mirror PUF.
Salomon Adi
We report that Para-Red, a long known azo dye not previously recognized as forming a nonlinear optically (NLO) active crystal, exhibits strong second harmonic generation (SHG) when crystalized in an appropriate morphology. Using a controlled vapor-deposition process, we obtain plate-like crystals of the Pn polymorph that expose the (020) plane, whose orientation lies close to the molecular packing axis associated with the dominant hyperpolarizability direction. In contrast, the traditionally solution grown needles of the same polymorph expose planes nearly orthogonal to the optical axis and therefore appear NLO-inert. The vapor-grown plates produce clean and robust SHG without the need for cutting or polishing and can be exfoliated into thin layers suitable for integration. These results reveal a previously hidden NLO response in Para-Red and demonstrate that morphology-controlled crystal growth can enable NLO in other previously discarded organic materials.
Desiatov Boris
he invention relates to a hybrid optical phased array (OPA) platform combining thin-film lithium niobate (TFLN) photonic circuits with three-dimensional polymer end-fire antennas fabricated using two-photon polymerization. The architecture enables compact, broadband, and high-speed optical beam steering by integrating electro-optic phase control with elevated 3D antenna arrays. The technology is suitable for applications including LiDAR, free-space optical communication, and adaptive photonic systems.
Aurbach Doron
We intend to prepare and optimize anodes in rechargeable aqueous Na ions batteries for large & safe energy storage. The invention includes selection of appropriate redox polymers add to it carbon nanotubes, thus preparing stand-alone composite electrodes. We will select also appropriate electrolyte solutions, and will optimize parameters in prototype Na ion cells.
Noked Malachi
Zinc–bromine batteries (ZBBs) are promising candidates for large-scale energy storage due to their low cost, inherent safety, and high theoretical energy density. However, conventional flow-based ZBBs suffer from low system-level energy density and operational complexity. Recent interest has shifted toward flowless ZBBs (FL-ZBBs) configuration, yet these face critical challenges associated with uncontrolled diffusion and self-discharge (SD) of bromine species at the cathode. One of the holy grails in addressing these challenges is the use of quaternary ammonium salts (NR₄⁺), which interact with bromine species to inhibit their diffusion. In this work, through a targeted localized presence (TLP) approach, wherein bromine-complexing agents (BCAs) are impregnated directly into porous carbon cathodes, we demonstrate that phosphonium-based BCAs, particularly tetrabutylphosphonium bromide (TBP), outperform traditional ammonium-based analogs in FL-ZBBs. TBP enables high Coulombic efficiency (>98.5%, 1 A g⁻¹) for 145 mAh g⁻¹, reduces the SD phenomenon, and achieves long-term cycling stability of over 500 cycles with >97% CE (1.5 A g⁻¹, 145 mAh g⁻¹), even under low electrolyte concentrations (0.5M ZnBr2). The enhanced performance is attributed to faster 2Br⁻/Br₂ redox kinetics, as demonstrated by cyclic voltammetry, and improved molecular polybromide∙∙∙PR₄⁺ interactions, highlighting phosphonium salts as more attractive BCA compounds for high-performance FL-ZBBs.
